Interface to National Library of Medicine MESH SPARQL endpoint to obtain the pharmacological action of a medication, using the following type of query:
PREFIX rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#>
PREFIX rdfs: <http://www.w3.org/2000/01/rdf-schema#>
PREFIX xsd: <http://www.w3.org/2001/XMLSchema#>
PREFIX owl: <http://www.w3.org/2002/07/owl#>
PREFIX meshv: <http://id.nlm.nih.gov/mesh/vocab#>
PREFIX mesh: <http://id.nlm.nih.gov/mesh/>
PREFIX mesh2020: <http://id.nlm.nih.gov/mesh/2020/>
PREFIX mesh2019: <http://id.nlm.nih.gov/mesh/2019/>
PREFIX mesh2018: <http://id.nlm.nih.gov/mesh/2018/>
PREFIX : <urn:ex:>
SELECT DISTINCT ?paLabel
FROM <http://id.nlm.nih.gov/mesh>
WHERE {
?s ?p ?n .
?possible_concepts (:|!:){,3} ?s .
BIND (?possible_concepts as ?fresh_possible_concepts) .
?fresh_possible_concepts (:|!:){,3} ?n .
?fresh_possible_concepts rdf:type meshv:TopicalDescriptor .
?fresh_possible_concepts meshv:pharmacologicalAction ?pa .
?pa rdfs:label ?paLabel .} 'Compare the results obtained via MESH with results obtainable via US FDA National Drug Code (NDC) Directory data:
MESH results for ‘Stribild’:
- Anti-HIV Agents
US FDA NDC results for ‘Stribild’:
- Mechanism of Action
- HIV Integrase Inhibitors
- Cytochrome P450 2C9 Inducers
- Cytochrome P450 3A Inhibitors
- P-Glycoprotein Inhibitors
- Cytochrome P450 2D6 Inhibitors
- Organic Anion Transporting Polypeptide 1B1 Inhibitors
- Organic Anion Transporting Polypeptide 1B3 Inhibitors
- Breast Cancer Resistance Protein Inhibitors
- Nucleoside Reverse Transcriptase Inhibitors
- Nucleoside Reverse Transcriptase Inhibitors
- Established Pharmacological Class
- Human Immunodeficiency Virus Integrase Strand Transfer Inhibitor
- Cytochrome P450 3A Inhibitor
- Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor
- Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor
- Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor
- Chemical Structure
- Nucleosides